Journal of IiMER May 2025 diseases. His expertise includes designing computational workflows that combine genomics, transcriptomics, proteomics, and metabolomics data to identify disease drivers and potential therapeutic targets. In the context of ME/CFS, in silico models are essential for handling the vast and heterogeneous datasets generated by modern research. Dr Modos’s work enables researchers to visualise and interpret complex biological interactions, predict disease-associated pathways, and prioritise hypotheses for experimental validation. This approach supports precision medicine by identifying patient subgroups and informing personalised treatment strategies. At BRMEC14, Dr Modos will present on the application of in silico models in ME/CFS research, demonstrating how computational analysis can accelerate biomarker discovery, improve disease stratification, and guide the development of targeted therapies. His contribution is particularly valuable for translating big data into actionable biological insights in ME/CFS and related complex diseases. Dr Modos will present computational (in silico) models that simulate biological processes in ME/CFS, aiding in hypothesis generation and the design of experimental studies. Dr Vicky Whittemore, Program Director in the National Institute of Neurological Disorders and Stroke at the National Institutes of Health in the United States IIMEC17: Hinxton Criteria Dr Vicky Whittemore is a Program Director in the Synapses, Channels and Neural Circuits Cluster at the National Institute of Neurological Disorders and Stroke (NINDS), part of the US National Institutes of Health (NIH). She oversees a portfolio of research grants focused on neurological conditions, including ME/CFS, and plays a key role in coordinating NIH efforts to advance biomedical research into this complex disease. Dr Whittemore holds a PhD in anatomy from the University of Minnesota, followed by postdoctoral training at the University of California, Irvine, and a Fogarty Fellowship at the Karolinska Institute in Stockholm. She was previously on the faculty at the University of Miami School of Medicine, working with The Miami Project to Cure Paralysis, and has held leadership roles in several non-profit organisations including the Tuberous Sclerosis Alliance and Citizens United for Research in Epilepsy (CURE). She also served a four-year term on the National Advisory Neurological Disorders and Stroke Council. Recently, Dr Whittemore led the NIH Roadmap for ME/CFS project, overseeing programme development and management. She supports collaborative research initiatives and promotes multidisciplinary approaches to improve understanding of ME/CFS. A regular speaker at Invest in ME Research’s international conferences, she facilitates scientific exchange between US and European researchers. Invest in ME Research Page 33 of 43
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