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Journal of IiMER May 2025 At IIMEC17, Dr Whittemore will discuss the Hinxton Criteria, which emerged from the 2024 Biomedical Research into ME Colloquium (BRMEC13) held at Hinxton Hall. This collaboration between NIH researchers, Invest in ME Research, and the European ME Research Group (EMERG) aims to establish refined diagnostic criteria and research standards for ME that reflect current scientific knowledge and encourage international cooperation. The Hinxton Criteria are distinct from the earlier International Consensus Criteria (ICC) and represent a complementary approach to diagnosis. Dr Jesper Mehlsen, Copenhagen University Hospital, Denmark IIMEC14:European Protocol for Pathobiology, Diagnosis, and Treatment of ME Dr Jesper Mehlsen graduated as a medical doctor in 1979 and finished his specialist training in 1990. He has published more than 140 scientific papers in peer reviewed journals, mainly on the autonomic nervous system and more recently on complex diseases possibly resulting form HPV-vaccination. For over 35 years, he has worked clinically and in research with dysfunction of the autonomic nervous system. Such dysfunction may lead to symptoms from a number of different organs often dominated by diminished control of blood pressure and heart rate. Over the past 5 years, he has worked clinically and in research with patients who suspect side effects due to HPV vaccination to be the cause of a number of symptoms, common to those seen in chronic ME. Dr Mehlsen is co-chair of the European ME Research Group (EMERG). Dr Mehlsen ran a clinic for ME patients in Copenhagen, Denmark, until recently where he provided clinical care and applies his research insights to patient management. He has been actively involved in developing a European consensus on treatment protocols for ME/CFS, aiming to establish standardised approaches that can be adopted across clinical settings. His research interests include methods for studying autonomic cardiovascular control, mathematical modelling of cardiovascular responses, and the neuroinflammatory reflex. Dr Mehlsen is also involved in discussions on clinical trials and standards within the ME research community, including chairing sessions at the Biomedical Research into ME Colloquium (BRMEC13). His work integrates clinical observation with advanced physiological and mathematical analyses to explore the underlying mechanisms of ME and related disorders. Invest in ME Research Page 34 of 43

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