Journal of IiME Volume 3 Issue 1 www.investinme.org Similarities of ME/Chronic Fatigue Syndrome (ME/CFS) and Autism Spectrum Disorders (ASD): Comparisons of Co-Infections (continued) minimal significance. Odds Ratios were calculated using logistic regression (Logit method) Statistica 5.5 (Statsoft, Tulsa, OK). In some cases, Pearson Chi-Square test was performed to compare prevalence data between patients and control subjects. Bacterial and Viral Infections: Using the blood of CFS patients (n=100) and PCR procedures an overwhelming majority of patients showed evidence of multiple, systemic bacterial and viral infections (Odds Ratio=18.0, p<0.001).17 CFS patients had a high prevalence (51%) of one of four Mycoplasma species (Odds Ratio=13.8, p<0.001) and often showed evidence of co-infections with different Mycoplasma species, C. pneumoniae (8%, Odds Ratio=8.6, p<0.01) and active HHV6 (30%, Odds Ratio=4.5, p<0.001) (Table 3). Evidence for Mycoplasma spp. infections was found in 28/48 or 58.3% of ASD patients and RESULTS Patient Demographic Data: These are shown in Tables 1 and 2. TABLE 1. CFS Patient demographic data. n Mean age (SD) Patients Controls Female patients Male patients 100 100 72 28 39.7 (8.9) 34.6 (9.1) 39.8 (9.8) 39.2 (10.3) Range Males (%) 18-66 21-58 18-66 20-60 28 (28) 31 (31) 0 (0.0) 28 (100.0) TABLE 2. ASD Patient demographic data. n Mean age (SD) Range Males (%) Patients Controls 48 45 Rural patients 18 Urban patients 30 8.4 (2.8) 7.9 (3.3) 8.1 (2.9) 8.6 (3.2) Invest in ME (Charity Nr. 1114035) 3-14 4-11 3-14 4-14 36 (75) 28 (62.2) 14 (77.7) 22 (73.3) Females (%) 72 (72) 69 (69) 72 (100.0) 0 (0.0) Females (%) 12 (25) 17 (37.8) 4 (22.3) 8 (26.7) Page 16/76
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