Journal of IiMER May 2025 BRMEC14 Session: Metabolism Body and Cell Session Chair: Rikke Olsen Aarhus Universitet, Denmark Dr Rikke Katrine Jentoft Olsen is Associate Professor at the Department of Clinical Medicine, Research Unit for Molecular Medicine, Aarhus University. She holds a master’s degree in molecular biology and a PhD in medicine. Her research focuses on the molecular genetics and cellular pathology of inborn errors of metabolism, with particular emphasis on fatty acid oxidation disorders and mitochondrial dysfunction. She integrates genetic diagnostics with studies of cellular mechanisms and the development of novel treatments, including mitochondrial vitamins and cofactors. In recent years, Dr Olsen has initiated research programmes investigating the role of mitochondrial and metabolic dysfunction in post-inflammatory fatigue, specifically in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). She is actively involved in clinical and research networks, serving on the boards of the International Network for Fatty Acid Oxidation Research and Management (INFORM) and the European ME Research Group (EMERG). Dr Olsen also contributes to the Danish Neonatal Screening Programme for inborn errors of metabolism. At the conference, Dr Olsen will chair the session on metabolic pathways in ME/CFS, drawing on her extensive background in mitochondrial medicine and metabolic research to guide discussions on recent advances and their implications for diagnosis and treatment. Chris Armstrong University of Melbourne, Australia BRMEC14: Mitochondrial Dysfunction in ME: Insights from Metabolomics and Precision Medicine Dr Armstrong will present metabolomic data revealing mitochondrial dysfunction and altered energy metabolism in ME/CFS. His research aims to identify metabolic biomarkers and inform precision medicine approaches for diagnosis and therapy. Dr Christopher Armstrong, from the Department of Biochemistry and Molecular Biology at the University of Melbourne, Victoria, Australia, will be presenting in the Metabolism Body and Cell session at BRMEC14. His research focuses on applying metabolomics techniques to understand the biochemical alterations in ME patients. As a leading researcher in ME metabolism, Dr Armstrong has made significant contributions to the field since publishing the first metabolomics paper on ME in 2015. His work explores various aspects of metabolism in ME, including energy metabolism, amino acid metabolism, and oxidative stress. Dr Armstrong's presentation is expected to provide insights into the metabolic underpinnings of ME, potentially shedding light on the disease's pathogenesis and opening avenues for future diagnostic and treatment strategies. Invest in ME Research Page 27 of 43
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