Journal of IiMER May 2025 BRMEC14 Session: Nervous System and Neuroinflammation Session Chair: Jonas Bergquist (University of Uppsala, Sweden / EMERG) Professor Bergquist will moderate talks on neuroinflammation and nervous system dysfunction in ME/CFS. Stuart Bevan (Kings College London, UK) BRMEC14: Sensory Symptoms in Post-Covid Syndrome (PCS) Patients with Pain and Fatigue Professor Stuart Bevan is Professor of Pharmacology at King’s College London and an internationally recognised expert in sensory neuroscience and pain research. With a scientific career spanning several decades, he has made significant contributions to understanding how sensory signals are detected and transmitted by peripheral sensory neurons. His research has focused on the molecular and cellular mechanisms underlying pain, including the roles of ion channels such as TRPV1, TRPM8, and TRPA1 in mediating responses to heat, cold, and chemical stimuli. Before joining King’s College London, Professor Bevan spent 20 years as Head of Pain Research at Novartis, where he led efforts to identify new analgesic targets and advance pain therapeutics. He has collaborated extensively with clinical researchers to investigate pain mechanisms in conditions such as osteoarthritis, fibromyalgia, and neuropathic pain. Professor Bevan has published widely in leading scientific journals and is known for his work on the pharmacology of sensory neurons and the development of novel approaches to pain management. At BRMEC14, he will present research on sensory symptoms in Post-Covid Syndrome patients with pain and fatigue, exploring the overlap with ME/CFS and discussing potential shared mechanisms and therapeutic strategies. His expertise provides valuable insight into the biological basis of sensory dysfunction in chronic illness. Denise Visser (University Medical Center Utrecht, Netherlands) Dr Denise Visser is a postdoctoral researcher at University Medical Center Utrecht, specialising in neuroimaging and neuroinflammation. Her research uses advanced PET imaging to investigate brain inflammation and molecular changes in neurological conditions, including studies on tau pathology and cerebral blood flow in neurodegenerative diseases, with a focus on glial cell activity. BRMEC14: Neuro-PET Data of Post-COVID Patients At BRMEC14, Dr Visser will present neuro-PET data from post-COVID patients, highlighting evidence of neuroinflammation. Her findings provide insight into the neurological effects of post-COVID syndrome and may reveal mechanisms shared with ME/CFS, supporting a deeper understanding of these conditions. Invest in ME Research Page 20 of 43
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