Journal of IiMER OUR CURRENT FUNDING STREAMS The UK Centre of Excellence for ME Support for the UK Centre of Excellence for ME will provide a solid foundation for high-quality biomedical research into ME. This approach to research will change the landscape for research into ME and make this an area of research that will encourage innovation and novel research. Rituximab Trial/B-Cell Research The B-cell/Rituximab research. The charity is keen to replicate the recent Norwegian findings using Rituximab. We initiated B-cell research at UCL leading to a UK rituximab clinical trial. A specific web site has been set up to document this project – see www.ukrituximabtrial.org. Gut Microbiota Related Projects Beginning with our foundation project at Norwich Research Park. It is not often realised that 60-70% of the immune system is located in the gut as a vast network of lymph tissue referred to as GALT (gut associated lymphatic tissue). The research highlighted in the proposal involves looking at gut microbiota, which is some of the latest thinking in how to go about research. A foundation project at the University of East Anglia began in 2013 - funded by the charity. Medical Students Part of the charity's strategy for improving education has been to involve medical students in research into ME. By participating in the research projects funded by the charity then students are able to learn far more about ME and patients as well as passing on the reality of this disease to their peers. www.investinme.org Page 14 of 82

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