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Journal of IiME Volume 8 Issue 1 After 2 years studying neuropeptides, he joined Dr Peter Barnes' laboratory at the National Heart and Lung Institute, Brompton Hospital, London, UK. Dr Baraniuk returned to Washington, DC, and Georgetown University, where he is currently Associate Professor with Tenure in the Department of Medicine. #IIMEC9 Abstract: Brain Imaging and ME Not available at time of printing – but will be made available on Invest in ME web site. Professor Julia Newton Clinical Professor of Ageing and Medicine, Institute for Ageing and Health, Newcastle University and Honorary Consultant Physician, Royal Victoria Infirmary, UK Professor Newton's research programme focuses upon the integrity of the autonomic nervous system in health and disease, specifically the role of autonomic dysfunction in the pathogenesis of fatigue and its clinical consequences, namely cognitive impairment. Examining the integrity of the ANS in humans is established in her physiology laboratory using relatively simple, inexpensive, non-invasive technologies that allow evaluation of a wide range of parameters that will within the foreseeable future be readily transferable into therapeutic interventions for patients. #IIMEC9 Abstract: ANS and ME Autonomic Dysfunction & ME The autonomic nervous system controls all of those functions that go on in the human body outside conscious control. Studies have confirmed that problems with the autonomic nervous system (autonomic dysfunction (AD)) are a common occurrence in those with ME, with almost 90% of sufferers describing postural dizziness, syncope (blackouts) and a range of other autonomic symptoms. Formal testing has confirmed the presence of objectively measured autonomic May 2014 dysfunction in ME with conditions such as neurally mediated hypotension and positional tachycardia syndrome recognised at significantly increased prevalence compared to matched control populations. The underlying cause of this frequently found AD is as yet not understood. Studies will be described confirming muscle, cardiac and brain abnormalities the severity of which associates with the underlying AD. Professor Maureen Hanson Liberty Hyde Bailey Professor, Cornell University Maureen Hanson is Liberty Hyde Bailey Professor in the Department of Molecular Biology and Genetics at Cornell University in Ithaca, NY. Previously she was on the faculty of the Department of Biology at the University of Virginia in Charlottesville and an NIH NRSA postdoctoral fellow at Harvard, where she also completed her Ph.D. degree. While most of her prior research has concerned cell and molecular biology in plant cells, she began a research program on ME/CFS after noting at a 2007 IACFS meeting the paucity of molecular biologists studying the illness. Her lab was part of the 2012 multicenter study organized by Ian Lipkin's group at Columbia University to assess the actual role of XMRV in ME/CFS. Dr. Hanson has a current project to examine the microbiome of ME/CFS patients and controls, in collaboration with Dr. Ruth Ley (Cornell Microbiology) and Susan Levine, M.D. (Manhattan, NY). Dr Levine is also collaborating with Dr. Hanson on an immune cell gene expression project that involves Dr. Fabien Campagne and Dr. Rita Shaknovich at Weill Cornell Medical School in New York City. Dr. Hanson's third project concerns analysis of blood samples from individuals performing a twoInvest in ME (Charity Nr. 1114035) www.investinme.org Page 45 of 52

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