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Journal of IiME Volume 6 Issue 1 (June 2012) to observe his own brain in real time. In this way it is possible to observe brain pulsations as well as blood flow through meningeal arteries. We hypothesize that direct observation of the brain triggers a bio-feedback effect. Figure 2. Two dimension image of the temporal region. The skin layers and the temporal muscle are clearly visible. The temporal squama appears as an hyperreflecting (white) irregular line of about 1.4 mm thickness. The meninges appear as a well organized array of layers of about 5 mm thickness. The sub-arachnoidal space (white arrow) is identified by two hyper-reflecting (white) lines sandwiching an hypo-reflecting (black) space containing liquor. The size of the sub-arachnoidal space was about 0.6 mm. The neuronal layers of the temporal cortex (3.8 mm thickness) appear as alternate layers of hyper- and hypo-reflecting structures. The thickness of the cortex corresponds to that of the TE and TG areas. Figure 4. Two dimension image of the left biceps brachii. Also in this case the operator applied the probe to his own biceps. A. Thickness of the relaxed biceps 10 min before the procedure; 24.9 mm. B. Thickness of the contracted biceps 10 min before the procedure; 38.3 mm. C. Thickness of the relaxed biceps 10 min after the procedure; 24.9 mm. Please notice; this image is not the same shown in panel A, as clearly visible looking at the orientation of the fibres. Nevertheless, the measurement is identical, thus demonstrating the reproducibility of the procedure. D. Thickness of the contracted biceps 10 min after the procedure; 43.2 mm. References 1. Carruthers BM, van de Sande MI, De Meirleir KL, et al. Myalgic encephalomyelitis: International Consensus Criteria. Journal of Internal Medicine. 2011; 270: 327-38. 2. Holgate ST, Komaroff AL, Mangan D et al. Chronic fatigue syndrome: understanding a complex illness. Nature Reviews Neuroscience. 2011;12: 539-44. 3. Hughlings Jackson, J. (1884). In: J. Taylor (Ed.), Selected Writings of John Hughlings Jackson. Evolution and Dissolution of the Nervous System. Vol. 2, pp. 3-118. Basic Books, New York. Figure 3. Pulsating arterial blood vessels in the meninges. 4. Roofe, PG and Matzke, HA. (1968). In: J. Minkler (Ed.), Pathology of the Nervous System. Introduction to the study of evolution: its relationship to neuropathology. Vol. 1, pp.14-22. Blakiston, New York. Invest in ME (Charity Nr. 1114035) www.investinme.org Page 27 of 108

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