Journal of IiME Volume 4 Issue 1 www.investinme.org Definition of Recovery in Chronic Fatigue Syndrome (continued) childhood: relation to Epstein-Barr virus. In: Ablashi D, editor. Epstein-Barr Virus and Human Disease; 1989 1989; Rome, Italy: Humana Press; 1989. p. 412-7. 6. Bell D, Bell K, Cheney P. Primary Juvenile fibromyalgia syndrome and chronic fatigue syndrome in adolescents. Clin Inf Dis. 1994;18(Suppl 1):S21-S3. 7. Bell D, Jordan K, Robinson M. Thirteen-year follow-up of children and adolescents with chronic fatigue syndrome. Pediatrics. 2001;107(5):994-8. 8. Reeves W, Wagner D, Nisenbaum R, Jones F, Gurbaxani L, Solomon L, et al. Chronic fatigue syndrome - A clinically empirical approach to its definition and study. BMC Medicine. 2005;3:http://www.biomedcentral.com/17417015/3/19. 9. Ware N, Sherbourne C. The MOS 36-Item Short Form Health Survey. Medical Care. 1992;30:473-83. 10. Fisk J, Ritvo P, Ross L, Haase D, Marrie T, Schlech W. Measuring the functional impact of fatigue: initial validation of the fatigue impact scale. Clin Infect Dis. 1994;Suppl 1:S79-S83. 11. Bell D, editor. The Doctor's Guide to Chronic Fatigue Syndrome. Reading, MA: Perseus Books; 1993. 12. Myhill S, Booth N, McLaren-Howard J. Chronic fatigue syndrome and mitochondrial Table 1: Comparing equality of means between "recovered" ME/CFS and control subjects Clinical Assessment Tool Patient Status Std. Fisk FIS Control VAS Total Recovered Control Hours of Activity Bell Ability Scale Recovered Control Recovered Control Recovered Invest in ME (Charity Nr. 1114035) Number Mean 10 10 10 10 10 10 10 10 Deviation 4.00 22.80 6.10 19.80 15.50 14.00 99.00 90.00 5.812 25.828 4.630 14.673 1.667 1.944 3.162 12.472 Independent Samples T-Test: Std. Error Mean 1.838 8.167 1.464 4.640 .527 .615 1.000 3.944 Page 26/56 p = 0.040 2-Tailed Significance (Equal Variances Assumed) p = 0.038 p = 0.011 p = 0.080 dysfunction. Int J Clin Exp Med. 2009;2:1-16. 13. Komaroff A, Fagioli L, Doolittle T, Gandek B, Gleit M, Guerriero T, et al. Health status in patients with the chronic fatigue syndrome and in general population and disease comparison groups. Am J Med. 1996;101:281-90. 14. Buchwald D, Pearlman T, Umali J, Schmaling K, Katon W. Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. Am J Med. 1996;171:364-70. 15. Lombardi V, Ruscetti F, Gupta J, Pfost M, Hagen K, Peterson D, et al. Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. . Science. 2009;326(5952):595-89. 16. Jason L, Richman J, Rademaker A, al e. A community-based study of chronic fatigue syndrome. Arch Intern Med. 1999;159:212937. 17. Levine P. Epidemic neuromyasthenia and chronic fatigue syndrome: epidemiological importance of a cluster definition. Clin Infect Dis. 1994;18 (Suppl 1):S16-20. Appendix I: Bell Ability Scale (Ref: Bell DS. The Doctor's Guide to Chronic Fatigue Syndrome. Perseus Books, Reading, MA; 1993)

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