Journal of IiME Volume 2 Issue 1 www.investinme.org Facts on ME Improved Renal Function in CFS/ME Patients with IVIG By Dr Tae Park Dr Tae Park M.D. Dr.Park runs his own CFS clinic in Seoul, Korea. Dr. Park attended the Invest in ME International ME/CFS Conference in London in May 2007 and will be in attendance and briefly speaking at the IiME conference in May 2008 Objecitve of study: To prove the effectiveness of IVIG tx in CFS/ME patients. Method of study: The study was made by checking the GFR of 125 CFS/ME patients by s-creatinine clearance with cockcroft-gauld formula. There are several studies about the effectiveness of IVIG tx in CFS/ME patients. But there have been no reports as to how they improve. It has been known that CFS/ME is really an inflammatory disease of the CNS, mainly from micro-vasculitis. Also the immuneglobuline is the only drug to improve the CNS inflammation at the present time. Here we report that there is real measurable evidence to show that there is improved renal blood flow in CFS/ME patients with IVIG tx. We randomly selected 125 patients who met the 1994 Fukuda criteria . We found there were significant renal blood flow improvements in 60 patients (50%) with IVIG tx, . We also found significant improvement of patients’ sx, especially fatigue, sleep disorders, muscle pain and, most of all, they showed marked improvement in the cognitive functions. Among the improved cognitive functions displayed patients showed remarkable improvements in comprehension and concentrations. The improvement of renal blood flow are between 35% to 60% of previous GFR. These findings of improved renal blood flow may be evidence of improved cerebral blood flow. Furthermore, they may explain the improvement of cognitive functions and other symptoms of CFS/ME patients with IVIG tx. This study will lead to further investigation of CFS/ME tx with IVIG tx. Invest in ME (Charity Nr. 1114035) Order our free newsletter. Distributed monthly via html, plain text or PDF. Go to ttp://www.investinme.org/IIMENewslettersubs.htm There can be no doubt that NICE ignored the international evidence that ME/CFS is a biomedical, not psychiatric, disorder, claiming that studying this evidence fell out with its remit. Such a claim is mystifying, since knowledge of the existing evidencebase ought surely to be mandatory before producing a national Guideline on the management of any disorder, especially given that adherence to such a Guideline is obligatory throughout the NHS (and hence for affiliated agencies such as the Department for Work and Pensions and Social Services). - Margaret Williams ME Story I caught glandular fever and just afterwards in my nurse training found I was always getting tonsillitis. In 1996 I came down with a serious set of symptoms which included palpitations, chest pains and very sore joints. I was so ill that I was admitted to hospital with pericarditis. I was unable to walk for 6 weeks. I took ages to respond to treatment and over the next few months I was given so many blood tests which eventually concluded I had a virus from the enteroviral family related to polio - Sue Page 8/34
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