ISBN : 978-93-85073-24-3 high degree of functional specificity, thus allowing a degree of interaction between technology and biological systems not previously attainable. It should be appreciated that nanotechnology is not in itself a single emerging scientific discipline but rather a meeting of traditional sciences such as chemistry, physics material science and biology to bring together the required collective expertise needed to develop these noval technologies. Numerous nanoparticle-based drug delivery and drug targeting systems are currently developed or under development. Their use aims to minimize drug degradation upon administration, prevent undersirable side effects, and increase drug bioavailability and the fraction of the drug accumulated in the pathological area. Author wish that pharmaceutical drug carriers, especially the ones for parenteral administration, are expected to be easy and reasonably cheap to prepare, biodegradable, have small particle size, possess high loading capacity, demonstrate prolonged circulation, and, ideally, specifically or non-specifically accumulate in required pathological sites in the body. In conclusion, even a brief listing of some key problems of nanocarriermediated drug delivery to brain shows how broad and intense this area is. In addition to this, nanoscale-based delivery strategies are beginning to make a significant impact on BBB- targeting programe and also global pharmaceutical planning and marketing. References 1. V. P. Torchilin, J. Control. Rel., 73, 137, 2001 2. A. M. Fernandez, K. Van Derpoorten, L. Dasnois, K. Lebtahi, V. Dubois, T. J. Lobl, S. Gangwar, C. Oliyai, E. R. Lewis, D. Shochat, A. Trouet, J. Med. Chem., 44, 3750, 2001. 16
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