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Journal of IiME Volume 2 Issue 1 www.investinme.org WHO GETS ME AND WHY - The role of impaired capillary blood flow in ME (continued) REFERENCES 1. Marshall EP, Williams M, Hooper M. What is ME? What is CFS? December 2001. 2. Anonymous. The Nightingale myalgic encephalomyelitis (M.E.) definition. The Nightingale Research Foundation, Ottawa, Canada. January 29, 2007. 3. Carruthers BM. Definitions and aetiology of myalgic encephalomyelitis: how the Canadian consensus clinical definition of myalgic encephalomyelitis works J Clin Path 2007;60:117-9. 4. Simpson LO, Shand BI, Olds RJ. Blood rheology and myalgic encephalomyelitis: a pilot study. Pathology 1986;18:190-2. 5. Weed RI. The importance of erythrocyte 6. Simpson LO. deformability. Am J Med 1970;49: 147-50. Chronic tiredness and idiopathic chronic fatigue – a connection ? N J Med 1992;89: 211-6. 7. Simpson LO. Blood from healthy animals and humans contains nondiscocytic erythrocytes. Haematol 1989;73: 561-4. Br J 8. Simpson LO. Nondiscocytic erythrocytes in myalgic encephalomyelitis. NZ Med J 1989;102: 106-7. 9. Simpson LO. Red cell shape in health and disease. In: Swamy NVC, Megha Singh (eds) Physiological Fluid Dynamics III. Narosa Publishing House, New Delhi, 1992, pp 230-5. 10. Miller SE, Roses AD, Appel SH. Scanning electron microscopy studies in muscular dystrophy. Arch Neurol 1976; 33: 172-4. 11. Markesbery WR, Butterfield DA. Scanning electron microscope studies of erythrocytes in Huntington’s Disease. Biochem Biophys Res Commun 1977; 78: 560-4. 12. Tanahashi N, Meyer JS, Ishikawa Y, et al. Cerebral blood flow and cognitive testing correlate in Huntington’s Disease. Arch Neurol 1985; 42: 1169-75. 13. Mukherjee TM, Smith K, Maros K. Abnormal red cell morphology in myalgic encephalomyelitis. (letter) Lancet 1987;ii: 328-9. 14. Simpson LO. The role of nondiscocytic erythrocytes in the pathogenesis of myalgic encephalomyelitis/chronic fatigue syndrome. In: Hyde BM, Goldstein J, Levine P (eds) The clinical and scientific basis of myalgic encephalomyelitis/chronic fatigue syndrome. The Nightingale Research Foundation, Ottawa, Canada, 1992, pp 597-605. 15. Vandergriff KD, Olson JS. Morphological and physiological factors affecting oxygen uptake and Invest in ME (Charity Nr. 1114035) Information for clinicians and lawyers. release by red blood cells. J Biol Chem 1984; 259:12619-27. 16. Muscio B. Is a fatigue test possible ? A report to the Industrial Fatigue Research Board. Br J Psychol 1921;12: 31-46. 17. Ellis J. Malaise and fatigue. Symptoms that depress a doctor and should not. Br J Hosp Med 1984;32: 312-4. 18. Simpson LO. Red cell shape. (letter) NZ Med J 1993;106: 531. 19. Simpson LO, Murdoch JC, Herbison GP. Red cell shape changes following trigger finger fatigue in subjects with chronic tiredness and healthy controls. NZ Med J 1993;106: 104-7. 20. Griffiths M. An introduction to human physiology. New York, NY, MacMillan Publishing Co., Inc.,1981, pp 73-4. 21. Wiles CM, Jones DA, Edwards RHT. 22. Ffrench G. Fatigue in human metabolic myopathy. Ciba Symposium 1981;82: 26482. The clinical significance of tiredness. Canad MAJ 1960;82: 665-71. 23. Swank RL, Roth JG, Woody DC Jr. Cerebral blood flow and red cell delivery in normal subjects and in multiple sclerosis. Neurol Res 1983;5: 37-59. 24. Bench CJ, Frackowiak RS, Dolan RJ. Changes in regional cerebral blood flow on recovery from depression. Psychol Med 1995;25: 247-61. 25. Lucey JV, Costa DC, Adshead G, et al. Brain blood flow in anxiety disorders. OCD, panic disorder with agoraphobia and post-traumatic stress disorder on 99 TchMPAO single photon emission tomography (SPET). Br J Psychiatry 1997;171: 346-50. 26. Kury PG, Ramwell PW, McConnell HM. The effect of prostaglandin E1 and E2 on the human erythrocyte a monitored by spin labels. Biochim Biophys Res Commun 1974;56: 478-83. 27. Rasmussen H, Lake W, Allen JE. The effect of catecholamines and prostaglandins on rat and human erythrocytes. Biochim Biophys Acta 1975;411 63-73. ME Story I have never known how such an illness can be so debilitating and so destructive yet virtually ignored by so many people. It is awful. I hope one day to be free of the ignorance. - Paul Page 32/34

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