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Journal of IiME Volume 2 Issue 1 www.investinme.org “The identification of clinically significant subgroups is the logical next step in furthering ME-CFS research. There might be multiple pathways leading to the cause and maintenance of the neurobiologic disregulations and other symptoms experienced by individuals with MECFS. Depending upon the individual and subtype, these may include unique biological, genetic, neurological, and socioenvironmental contributions. Subgrouping is the key to understanding how ME/CFS begins, how it is maintained, how medical and psychological variables influence its course, and in the best case, how it can be prevented, treated, and cured. I have a paper on this that was published, and it goes into much more detail. [See "Exploratory subgrouping in CFS: Infectious, inflammatory, and other": [http://www.investinme.org/Documents/Journals/Journal%20of% 20IiME%20Vol%201%20Issue%201.pdf ] “ - Live Chat Q&A with Chronic Fatigue Syndrome Research and Policy Leader Dr. Leonard A. Jason, PhD http://www.immunesupport.com/library/showarticle.cfm/ID /8232 Invest in ME (Charity Nr 1114035) Page 2

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